Table 3

Factors associated with colorectal adenomas and advanced neoplasm in 380 subjects in the overall population

FactorsUnivariate analysisMultivariate analysis
OR (95% CI)p ValueOR (95% CI)p Value
Colorectal adenomas
 NAFLD1.93 (1.22 to 3.06)0.0051.61 (0.90 to 2.90)0.11
 Age (years)1.05 (1.01 to 1.08)0.0081.04 (1.01 to 1.08)0.020
 Male gender1.75 (1.11 to 2.74)0.0151.44 (0.88 to 2.36)0.15
 Smoking2.36 (1.29 to 4.32)0.0052.53 (1.32 to 4.85)0.005
 Colorectal cancer in first degree relatives2.03 (0.86 to 4.79)0.101.73 (0.69 to 4.35)0.25
 BMI (kg/m2)1.06 (1.01 to 1.12)0.0171.03 (0.97 to 1.10)0.30
 Diabetes1.22 (0.73 to 2.07)0.451.27 (0.69 to 2.35)0.44
 Hypertension1.73 (1.07 to 2.80)0.0260.75 (0.44 to 1.28)0.29
Advanced neoplasm
 NAFLD3.91 (1.88 to 8.11)<0.0013.04 (1.29 to 7.20)0.011
 Age (years)1.06 (1.02 to 1.11)0.0081.06 (1.01 to 1.11)0.013
 Male gender1.82 (0.98 to 3.39)0.0591.38 (0.70 to 2.71)0.35
 Smoking2.24 (1.06 to 4.75)0.0362.66 (1.16 to 6.10)0.021
 Colorectal cancer in first degree relatives0.66 (0.15 to 2.91)0.580.44 (0.09 to 2.12)0.31
 BMI (kg/m2)1.09 (1.03 to 1.16)0.0051.06 (0.98 to 1.15)0.16
 Diabetes1.75 (0.90 to 3.42)0.0990.89 (0.41 to 1.91)0.76
 Hypertension1.63 (0.86 to 3.10)0.141.06 (0.52 to 2.14)0.88
  • BMI, body mass index; NAFLD, non-alcoholic fatty liver disease.