Table 1

Summary of genetic variants mentioned in the text

GeneSNPCommon nameNucleotide variantProtein coding variant
NOD2rs2066844SNP8C2104TR702W
NOD2rs2066845SNP12G2722CG908R
NOD2rs2066847SNP133020insC*1007fs
ATG16L1rs2241880T→CT300A
IRGMrs13361189in 5′ UTR†
XBP1Multiple
ORMDL3rs2872507

  • ↵* 2939insC in mice.

  • ↵† In perfect linkage disequilibrium with 20 kb deletion polymorphism in IRGM promoter.