Table 3

Comparison of severity of symptoms between fructo-oligosaccharide (FOS) and placebo groups at baseline and during the 4-week trial period

Severity	Baseline^*	p Value	Trial score^†	p Value
Acid reflux
FOS	2.5 (3.6)		4.0 (2.8)
Placebo	3.0 (3.9)	0.487	2.8 (3.5)	0.218
Rumbling gut
FOS	7.7 (4.9)		8.3 (4.0)
Placebo	7.8 (5.3)	0.900	6.0 (6.9)	0.029
Abdominal bloating
FOS	8.8 (5.5)		9.6 (5.5)
Placebo	7.7 (5.7)	0.321	7.4 (4.6)	0.061
Abdominal pain
FOS	11.2 (4.8)		10.2 (5.2)
Placebo	10.8 (4.3)	0.667	8.0 (2.7)	0.048
Flatulence
FOS	8.3 (5.0)		10.8 (5.2)
Placebo	8.0 (5.5)	0.780	8.0 (4.7)	0.004

↵* Mean (SD) cumulative score over a 7-day period using the following scoring system: 0=absent; 1=mild; 2=moderate; 3=severe.
↵† Mean cumulative average score for the 4-week trial period.