Table 3

Multivariate analyses on RR of baseline characteristics for recurrent colorectal neoplasia

Any adenomaAdvanced adenoma
HR (95% CI)*p ValueHR (95% CI)*p Value
Aged 60–69 (vs 50–59)1.99 (1.60 to 2.47)<0.0011.51 (0.86 to 2.65)0.153
Male1.59 (1.26 to 1.99)<0.0011.00 (0.57 to 1.77)0.980
Family history of colorectal cancer1.18 (0.83 to 1.69)0.3611.14 (0.48 to 2.76)0.761
BMI ≥25 kg/m20.92 (0.60 to 1.22)0.4871.10 (0.74 to 1.35)0.611
Abdominal obesity1.02 (0.86 to 1.22)0.8231.06 (0.70 to 1.59)0.790
Current smoking (vs never)1.25 (0.96 to 1.56)0.0601.55 (0.97 to 2.50)0.075
Alcohol consumption1.30 (1.06 to 1.60)0.0151.21 (0.76 to 1.92)0.425
Aspirin and/or NSAID use0.87 (0.68 to 1.09)0.2321.00 (0.59 to 1.71)0.693
Statin use0.96 (0.46 to 1.50)0.5021.02 (0.55 to 1.38)0.721
College graduate1.06 (0.49 to 2.12)0.7651.05 (0.62 to 1.46)0.603
High economic status1.36 (0.71 to 2.33)0.3041.20 (0.78 to 1.96)0.526
Adenoma characteristics
 ≥3 adenomas (vs 1 or 2)1.87 (1.47 to 2.37)<0.0013.06 (1.51 to 6.57)<0.001
 ≥10 mm adenoma (vs <10 mm)0.80 (0.57 to 1.13)0.2203.02 (1.80 to 5.06)<0.001
 With villous feature (vs no villous component)0.62 (0.42 to 0.93)0.0271.48 (0.74 to 2.95)0.189
Risk category
 Low-risk group (vs normal group)1.93 (1.58 to 2.36)<0.0011.14 (0.61 to 2.17)0.686
 High-risk group (vs low-risk group)2.70 (2.17 to 3.35)<0.0015.95 (3.66-9.68)<0.001
  • * Models adjusted for all variables in the table.

  • >90 cm in men and >80 cm in women according to the WPRO waist circumference criteria.23

  • Monthly family income ≥US$5000.

  • BMI, body mass index; NSAID, non-steroidal anti-inflammatory drug.