Table 3

Clinical features of pancreatic NETs

TumourSymptoms
InsulinomaConfusion, sweating, dizziness, weakness, unconsciousness, relief with eating
GastrinomaZollinger–Ellison syndrome of severe peptic ulceration and diarrhoea, or diarrhoea alone23
GlucagonomaNecrolytic migratory erythema, weight loss, diabetes mellitus, stomatitis, diarrhoea
VIPomaVerner–Morrison syndrome of profuse watery diarrhoea with marked hypokalaemia
SomatostatinomaCholelithiasis, weight loss, diarrhoea and steatorrhoea, diabetes mellitus24
Non-syndromic pancreatic NETSymptoms from pancreatic mass and/or liver metastases
  • NET, neuroendocrine tumour; VIPoma, vasoactive intestinal peptide-secreting tumour.