Table 1

Presentation of gastrointestinal side effects: acute, subacute or chronic

AetiologyAcuteSubacuteChronic
Infection

  • Bacterial

  • Viral

  • Fungal

  • Opportunistic

Small bowel bacterial overgrowthSmall bowel bacterial overgrowth
Inflammation (acute)

  • Neutropenic enterocolitis

  • Perforation

  • Haemorrhage

  • Graft versus host disease

Pancreatic insufficiency		Graft versus host diseaseGraft versus host disease
Inflammation (chronic)Bowel obstruction/strictures, Pancreatic insufficiencyGraft versus host disease
Ischaemic/fibroticGastric outflow obstructionGraft versus host disease, Pancreatic insufficiency

  • Biliary strictures

  • Bowel obstruction

Enteropathy and loss of physiological functions

  • Graft versus host disease

  • Pancreatic insufficiency

MetabolicMalabsorptionHepatic insufficiencyMalabsorptionMalabsorption
Vascular (ischaemia)

  • Mesenteric vascular insufficiency

  • Mesenteric thrombosis

Veno-occlusive disease		Enteropathy and loss of physiological functions
Vascular (proliferative)Telangiectasia causing bleeding