Table 2

Association of miR-375 downregulation with clinicopathological features of 60 ESCC patients

Clinicopathological featuresTotal case (%)miR-375 expressionp Value
Negative (%)Positive (%)
Sex
 Male43 (71.67)76.7423.260.461
 Female17 (28.33)82.3517.65
Age, years
 ≤6623 (38.33)78.2621.740.617
 >6637 (61.67)78.3821.62
Clinical Stage
 Early stage (I–II)22 (36.67)56.4543.550.003*
 Advanced stage (III–IV)38 (63.33)92.17.9
Distant metastasis
 M046 (76.67)86.7913.21<0.0001
 M114 (23.33)14.2985.71
Tumour size
 ≤5 cm21 (35)89.6610.340.187
 >5 cm39 (65)68.7531.25
  • * Significant difference.

  • ESCC, oesophageal squamous cell carcinoma.