Table 1

Surgical outcomes, body weight and food consumption in the study population

Time pointsNumber of ratsNumber for NMR analysisNumber for UPLC-MS analysisNumber for faecal bacterial analysisBody weight (g)t-Test p valueFood intaket-Test p value
RYBG (g)
ShamBypassShamBypassShamBypassShamBypassShamBypassShamBypass
Week -1 (Pre-op)181818186600341.9±30.7346.6±35.80.7124.7±2.825.7±2.70.31
2 (Post-op)161516150066358.6±22.6288.6±29.1<0.00129.5±2.814.3±3.2<0.001
4 (Post-op)1615161500383.8±21.7275.6±25.4<0.00130.9±2.722.4±3.1<0.001
6 (Post-op)161416146600400.3±22.8270.9±32.7<0.00125.7±3.218.9±5.1<0.001
8 (Post-op)161416146666419.8±25.3259.1±36.1<0.00120.9±4.914.6±6.50.007
  • NMR, nuclear magnetic resonance; UPLC-MS, ultra-performance liquid chromatography-tandem mass spectrometry; RYGB, Roux-en-Y gastric bypass.