Table 2

Risk of acute pancreatitis with respect to smoking status, pack-years of smoking and duration of smoking cessation

	All cases		Non-gallstone-related		Gallstone-related
	RR^† (95% CI)	p Value	RR (95% CI)	p Value	RR (95% CI)	p Value
Smoking status^*
Never	1 (Ref)		1 (Ref)		1 (Ref)
Former	1.19 (0.97 to 1.46)	0.09	1.47 (1.11 to 1.94)	<0.01	0.95 (0.62 to 1.26)	0.76
Current	1.33 (1.07 to 1.66)	<0.01	1.83 (1.37 to 2.44)	<0.01	0.88 (0.70 to 1.29)	0.49
Pack-years of smoking^*
Never	1 (Ref)		1 (Ref)		1 (Ref)
Former
<20	1.14 (0.90 to 1.45)	0.27	1.36 (0.98 to 1.88)	0.07	0.96 (0.68 to 1.37)	0.83
≥20	1.33 (0.99 to 1.79)	0.06	1.78 (1.21 to 2.60)	<0.01	0.91 (0.55 to 1.50)	0.70
Current
<20	1.11 (0.80 to 1.54)	0.53	1.46 (0.95 to 2.23)	0.08	0.80 (0.47 to 1.36)	0.42
≥20	1.53 (1.17 to 2.01)	<0.01	2.29 (1.63 to 3.22)	<0.01	0.83 (0.51 to 1.34)	0.45
Smoking cessation^* (years)
Never	1 (Ref)		1 (Ref)		1 (Ref)
Years from smoking cessation
<10	1.37 (0.99 to 1.90)	0.06	1.95 (1.29 to 2.94)	<0.01	0.85 (0.48 to 1.49)	0.57
10–14.9	1.28 (0.83 to 1.96)	0.26	1.70 (1.00 to 2.91)	0.05	0.88 (0.43 to 1.82)	0.74
15–19.9	1.25 (0.83 to 1.89)	0.29	1.72 (1.03 to 2.87)	0.04	0.80 (0.39 to 1.66)	0.56
20–24.9	1.14 (0.75 to 1.74)	0.54	1.20 (0.66 to 2.15)	0.55	1.13 (0.62 to 1.66)	0.69
25–29.9	0.95 (0.58 to 1.54)	0.82	1.14 (0.61 to 2.15)	0.67	0.77 (0.36 to 1.66)	0.51
≥30	1.07 (0.77 to 1.50)	0.66	1.07 (0.67 to 1.73)	0.77	1.11 (0.69 to 1.77)	0.67

↵* All the analyses are adjusted for age, gender, body mass index, diabetes, educational level and monthly alcohol consumption.
↵† Multivariable adjusted rate ratios (RR) and the corresponding 95% CIs.