Table 1

Characteristics of the seven enrolled patients before and after MSCT

Patient number
1234567
Age33272627412425
SexMMFMFMF
DiagnosisCDCDCDCDUCUCUC
Disease duration (m)406120346211348
Extent of diseaseIleum and colonTerminal ileumIleum and coloncolonPancolitisPancolitisPancolitis
Previous treatment
  • CS

  • 5-ASA

  • CYC

  • Antibiotics

  • CS

  • MTX

  • SASP

  • Etanercept

  • CS

  • SASP

  • CYC

  • CS

  • SASP

  • Infliximab

  • Antibiotics

  • CS

  • SASP

  • MMF

  • CYC

  • 5-ASA

  • CS

  • SASP

  • 5-ASA

  • CS

  • SASP

  • 5-ASA

Therapies used within 3 months before MSCT
  • CS

  • CYC

  • Antibiotics

  • CS

  • SASP

  • CS

  • SASP

  • CS

  • CYC

  • CS

  • MMF

  • CYC

  • 5-ASA

  • CS

  • SASP

Baseline CDAI/CAI score2233352953788109
Baseline EIS/EAI score18.719.114.520.3798
Concomitant medication
  • CS

  • CYC

  • CS

  • SASP

  • CS

  • SASP

  • CS

  • CYC

  • CS

  • 5-ASA

5-ASA
  • CS

  • SASP

CDAI/CAI score at 3 months after MSCT187140126284255
EIS/EAI score after MSCTNA
  • 4.2

  • (4 months)

  • 3

  • (3 months)

NA
  • 5

  • (5 months)

9NA
Adverse eventsNANAFace hotNAInsomniaLow feverNA
  • 5-ASA, 5-aminosalicylic acid; CAI, Clinical Activity Index; CD, Crohn's disease; CDAI, Crohn's Disease Activity Index; CS, corticosteroids; CYC, cyclosporine; EAI, Endoscopic Activity Index; EIS, Endoscopic Index of Severity; m, month; MMF, mycophenolate mofetil; MSCT, mesenchymal stem cell transplantation; MTX, methotrexate; NA, not available; SASP, sulfasalazine; UC, ulcerative colitis.