Patient number | |||||||
1 | 2 | 3 | 4 | 5 | 6 | 7 | |
Age | 33 | 27 | 26 | 27 | 41 | 24 | 25 |
Sex | M | M | F | M | F | M | F |
Diagnosis | CD | CD | CD | CD | UC | UC | UC |
Disease duration (m) | 40 | 6 | 120 | 34 | 62 | 113 | 48 |
Extent of disease | Ileum and colon | Terminal ileum | Ileum and colon | colon | Pancolitis | Pancolitis | Pancolitis |
Previous treatment |
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Therapies used within 3 months before MSCT |
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Baseline CDAI/CAI score | 223 | 335 | 295 | 378 | 8 | 10 | 9 |
Baseline EIS/EAI score | 18.7 | 19.1 | 14.5 | 20.3 | 7 | 9 | 8 |
Concomitant medication |
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| 5-ASA |
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CDAI/CAI score at 3 months after MSCT | 187 | 140 | 126 | 284 | 2 | 5 | 5 |
EIS/EAI score after MSCT | NA |
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| 9 | NA |
Adverse events | NA | NA | Face hot | NA | Insomnia | Low fever | NA |
5-ASA, 5-aminosalicylic acid; CAI, Clinical Activity Index; CD, Crohn's disease; CDAI, Crohn's Disease Activity Index; CS, corticosteroids; CYC, cyclosporine; EAI, Endoscopic Activity Index; EIS, Endoscopic Index of Severity; m, month; MMF, mycophenolate mofetil; MSCT, mesenchymal stem cell transplantation; MTX, methotrexate; NA, not available; SASP, sulfasalazine; UC, ulcerative colitis.