E-cadherin-positive | E-cadherin-negative | |
No. of patients | 15 | 10 |
Mean (range) age (years) | 68.3 (53–82) | 62 (51–81) |
Men (%) | 73 | 70 |
Mean±SD tumour grade | 2.26±0.70 | 2.10±0.57 |
R0-resected | 14/15 | 10/10 |
pN0/pN1/pN2 | 0/14/0 | 2/8/0 |
M0/M1 | 12/3 | 10/0 |
Resection specimens were reviewed by a senior pathologist and tumour staging was assessed according to the American Joint Committee on Cancer classification system (TNM). Two patients showed interaortocaval lymph node metastasis; in one patient a liver metastasis was found intraoperatively. Tumour cohorts did not show relevant differences in differentiation grade.