Species associated with high Firmicutes:Bacteroidetes (FB) ratio irritable bowel syndrome (IBS) versus control split
| Species | Controls | Normal-like IBS | IBS cluster 1 | IBS cluster 2 | p Value |
| Most abundant in high FB ratio IBS-associated | |||||
| Eubacterium hallii | 0.74 (0.42–1.2) | 0.91 (0.78–1.52) | 4.59 (2.24–7.08) | 0.97 (0.57–1.66) | <0.0001 |
| Clostridium innocuum | 0.0048 (0–0.0087) | 0.0078 (0.0034–0.0144) | 0.0428 (0.0242–0.0936) | 0 (0–0.004) | <0.0001 |
| Sporobacter termitidis* | 0.616 (0.179–1.02) | 0.448 (0.229–0.735) | 0.048 (0.009–0.327) | 1.48 (1.06–1.92) | <0.01 |
| Eubacterium desmolans | 0.095 (0.075–0.172) | 0.15 (0.053–0.258) | 0.398 (0.222–0.454) | 0.282 (0.133–0.767) | <0.01 |
| Eubacterium eligens | 0.483 (0.174–0.71) | 0.298 (0.015–0.834) | 0.0035 (0–0.0456) | 1.75 (0.0397–4.12) | <0.01 |
| Eubacterium siraeum* | 0.339 (0.028–1.16) | 0.285 (0.017–1.26) | 0.0043 (0–0.0182) | 0.457 (0.146–1.35) | <0.01 |
| Most abundant in control samples | |||||
| Odoribacter splanchnicus | 0.26 (0.12–0.49) | 0.15 (0.068–0.27) | 0.007 (0–0.042) | 0.104 (0.045–0.22) | <0.0001 |
| Alistipes putredinis | 3.44 (2.03–6.31) | 2.79 (1.67–4.45) | 0.59 (0.007–1.55) | 0.503 (0.095–1.15) | <0.001 |
| Barnesiella intestinihominis | 0.87 (0.24–1.92) | 0.22 (0.007–0.489) | 0.0027 (0–0.243) | 0.26 (0.1–0.67) | <0.001 |
| Bacteroides caccae | 0.33 (0.1–1.05) | 0.28 (0.006–0.596) | 0 (0–0.052) | 0.1 (0.018–0.175) | <0.01 |
| Bacteroides stercoris | 0.025 (0.0014–0.7) | 0 (0–0.0037) | 0 (0–0) | 0 (0–0.0153) | <0.01 |
Species showing significant differences in abundance across the four groups as defined from the Kruskal–Wallis analysis.
Values are shown as the median and associated IQR for the percentage of reads for the taxa in each group.
↵* Sporobacter termitidis and Eubacterium siraeum have both the highest and lowest values in the IBS clusters but are presented in this table as having their highest values in IBS cluster 2.