Table 2

Univariate and multivariate analysis of different prognostic parameters in 229 patients with CRC

VariableUnivariate analysis*Multivariate analysis
All casesMean survival (months)p ValueHR (95% CI)p Value
Sex0.675
 Female8776.7
 Male14274.6
Age at surgery, years0.943
 ≤57.310874.5
 >4512175.5
Tumour location0.688
 Colon17176.1
 Rectum5872.4
Histological grade (WHO)0.130
 G1–219377.4
 G33664.8
pT status0.0000.002
 T1–T29284.91.0
 T3–T413768.72.282 (1.347 to 3.864)
pN status0.0000.784
 N016980.31.0
 N1–N26063.41.194 (0.337 to 4.229)
pM status0.0000.016
 pMX20680.51.0
 pM12328.24.574 (1.333 to 15.689)
Clinical stage0.0000.312
 I–II15086.51.0
 III–IV7955.42.073 (0.504 to 8.529)
EIF5A2 expression0.0000.009
 Normal expression12783.31.0
 Overexpression10264.12.241 (1.227 to 4.095)
  • * Log-rank test.

  • Cox regression model.

  • Mean age.

  • CRC, colorectal carcinoma.