Table 1

Effect of dietary haem on faecal parameters and mucosal proliferation

ControlHaem
Faeces
 Cytotoxicity of faecal water (% lysis)23.0±2.4102.0±6.6*
 Faecal output (g wet weight/day)0.25±0.030.58±0.04*
Mucosa
 Total number of cells per crypt45.5±2.161.1±2.5*
 Number of Ki67-positive cells per crypt20.7±1.838.7±2.1*
 Labelling index† (%)44.9±2.062.9±1.0*

  • Data are presented as mean±SEM.

  • ↵* p<0.05.

  • ↵† Calculated as percentage Ki67-positive cells per crypt.