Table 1

Correlation between expression of EIF5A2 and clinicopathological features in 229 cases of CRC

All casesEIF5A2 protein
Normal expressionOverexpressionp Value*
Sex0.373
 Female8745 (51.7%)42 (48.3%)
 Male14282 (57.7%)60 (42.3%)
Age at diagnosis, years0.408
 ≤57.310863 (58.3%)45 (41.7%)
 >57.312164 (52.9%)57 (47.1%)
Tumour location0.799
 Colon17194 (55.0%)77 (45.0%)
 Rectum5833 (56.9%)25 (43.1%)
Histological grade (WHO)0.309
 G11911 (57.9%)8 (42.1%)
 G217492 (52.9%)82 (47.1%)
 G33624 (66.7%)12 (33.3%)
pT status0.122
 11612 (75.0%)4 (25.0%)
 27640 (52.6%)36 (47.4%)
 312973 (56.6%)56 (43.4%)
 482 (25.0%)6 (75.0%)
pN status0.002
 0169104 (61.5%)65 (38.5%)
 16023 (38.3%)37 (61.7%)
pM status0.003
 pMX206121 (58.7%)85 (41.3%)
 pM1236 (26.1%)17 (73.9%)
Clinical stage0.000
 I7447 (63.5%)27 (36.5%)
 II7653 (69.7%)23 (30.3%)
 III5621 (37.5%)35 (62.5%)
 IV236 (26.1%)17 (73.9%)
  • * χ2 test.

  • Mean age.

  • CRC, colorectal carcinoma; EIF5A2, eukaryotic initiation factor 5A2.