Mild-to-moderate 15-year CD | Severe 15-year CD | p Value | |
N | 279 | 321 | |
Close follow-up, % | 187 (67) | 208 (65) | NS |
Ever use of oral contraceptives, % | 54 (49)* | 82 (61)* | NS |
Any smoking, % | 121 (43) | 182 (57) | 0.001 |
Death related to CD, % | 0 | 23 (7) | NA |
Death unrelated to CD, % | 6 (2) | 6 (2) | NS |
Intestinal adenocarcinoma, % | 1 | 18 | <0.0001 |
Lymphoma, % | 1 | 1 | NS |
Other malignancies, % | 20 | 14 | NS |
No. of years with active disease | |||
0 | 89 (32) | 4 (1) | NA |
1 | 62 (22) | 6 (2) | |
2 | 69 (25) | 11 (3) | |
3 | 59 (21) | 17 (5) | |
4–5 | 0 | 108 (34) | |
6–10 | 0 | 134 (42) | |
>10 | 0 | 41 (13) | |
Changing behaviour, % | |||
B1 to B2 | 19 (12)* | 41 (18)* | <0.001 |
B1 to B3 | 18 (12)* | 56 (25)* | – |
B2 to B3 | 3 (7)* | 4 (11)* | NS |
Intestinal resection(s) | 61 (22) | 189 (59) | NA |
Delta PSHI | 0 (0–0) | 7 (0–21) | <0.01 |
Establishment of a permanent stoma | 0 | 42 (14)* | NA |
Proctological procedure(s) | 20 (8)* | 75 (24)* | <0.0001 |
All quantitative data are given as median (IQR).
↵* Per cent calculated in women of child-bearing age.
CD, Crohn's disease; NA, not applicable (item linked to the post hoc classification); NS, not significant percentage calculated in the appropriate subgroup of patients; PSHI, Post-Surgical Handicap Index.