Endoscopic disease activity indices for Crohn's disease
| Endoscopic score | Strengths | Weaknesses |
| CDEIS62 | Gold standard, fairly reproducible by trained endoscopists | Complex, time-consuming, difficult for beginners and daily routine, no definition of mucosal healing, inactive disease reflects absence of ulcers only |
| SES-CD63 | Simplified version with correlation to CDEIS, easier to use | One validation study only, less frequently used than CDEIS, no definition of mucosal healing |
| Rutgeerts score64 | Adapted for assessment of postoperative recurrence, prediction of clinical relapse of disease | No use outside of postoperative settings, used by few studies so far |
| Crohn's disease endomicroscopic activity score (CDEAS)67 | First score for in vivo histology, based on crypt structure, angiogenesis and inflammation assessment | One validation study only, special endomicroscopes and fluorescein administration required |
| Watson score* 68 | Three grades only, prediction of clinical relapse of disease, first score for functional in vivo imaging | One validation study only, special endomicroscopes and fluorescein administration required |
↵* Has also been used for ulcerative colitis.