Table 1

Regression and progression of histopathology by different treatment arms*

GroupNo changeRegression
nnOR (95% CI)*
Intention-to-treat analysis
 Placebo78991.00
 Anti-Hp+celecoxib591141.50 (0.97 to 2.32)
 Anti-Hp+placebo551261.80 (1.16 to 22.78)
 Celecoxib+placebo611201.55 (1.01 to 22.38)
Per-protocol analysis
 Placebo67821.00
 Anti-Hp+celecoxib47841.48 (0.91 to 2.40)
 Anti-Hp+placebo36962.19 (1.32 to 3.64)
 Celecoxib+placebo491021.72 (1.07 to 2.76)
  • * ORs and 95% CIs were calculated by logistic regression and adjusted for age, sex, smoking and drinking status.

  • The participants who remained H pylori positive.

  • The participants in whom H pylori was eradicated (negative by carbon-13 urea breath test after 45 days).