Table 4

Per-lesion sensitivity and positive predictive value (PPV) of various CT colonography (CTC) criteria for specifically diagnosing proximal synchronous cancer

Performance measures	Criteria for positive cancer diagnosis at CTC^*
Performance measures	Lesion size ≥10 mm	Lesion size ≥15 mm	Lesion size ≥20 mm	Lesion size ≥10 mm and uneven surface	Lesion size ≥10 mm and pericolic abnormality	Lesion size ≥10 mm and enlarged pericolic lymph nodes	Lesion size ≥15 mm and uneven surface, pericolic abnormality, or enlarged pericolic lymph nodes
Sensitivity, % (95% CI)	87.5 (50.8 to 99.9)	87.5 (50.8 to 99.9)	62.5 (30.4 to 86.5)	87.5 (50.8 to 99.9)	62.5 (30.4 to 86.5)	25 (6.3 to 59.9)	87.5 (50.8 to 99.9)
No. of lesions	7/8	7/8	5/8	7/8	5/8	2/8	7/8
PPV, % (95% CI)	17.5 (8.4 to 32.3)	70 (39.2 to 89.7)	100 (59.9 to 100)	33.3 (17.1 to 54.8)	100 (59.9 to 100)	100 (36.9 to 100)	77.8 (44.3 to 94.7)
No. of lesions	7/40^†	7/10	5/5	7/21	5/5	2/2	7/9

↵* Lesion size refers to the size measured on CTC.
↵† Forty lesions ≥10 mm were observed on CTC, including 33 prospectively and two retrospectively identified true lesions, and five false-positive lesions.