Table 2

Univariate and multivariate Cox proportional hazard regression analyses of OS in the VMP cohort (n=117)

UnivariateMultivariate
HR (95% CI)p ValueHR (95% CI)p Value
Gender (M or F)0.68 (0.34 to 1.38)0.291.07 (0.43 to 2.61)0.88
Age (>70)1.44 (0.97 to 2.9)0.31.68 (0.72 to 3.9)0.22
AJCC stage (I, II, III, IV)3.6 (2.24 to 5.79)1.16×1072.9 (1.82 to 4.93)1.59×105
Grade (1, 2, 3)1.72 (0.8 to 3.69)0.162.31 (1.03 to 5.2)0.04
Gene signature (A or B)2.1 (1.0 to 4.3)0.0363.08 (1.33 to 7.14)0.008
  • AJCC, American Joint Committee on Cancer; F, female; M, male; OS, overall survival; VMP, Vanderbilt and Max Planck.