Endomicroscopic features of local barrier dysfunction in IBD and controls
| Crohn's disease | Ulcerative colitis | Controls | p Value* | |
| Patients (N) | 7 | 6 | 12 | NA |
| Average number of optical biopsies | 33.8 | 42.1 | 36.6 | NS |
| Gaps (%) | 8.6±1.3 | 8.2±2.1 | 2.5±0.9 | <0.0001 |
| Microerosions (%) | 1.8±0.6 | 1.4±0.7 | 0.1±0.03 | <0.0001 |
| Fluorescein leakage (% of optical biopsies) | 32.4±9.3 | 28.9±7.2 | 4.2±3.1 | <0.0001 |
% Gaps and microerosions refer the proportion of the perimeter of epithelial surface with gaps or microerosions.
↵* p Value: t test IBD patients (Crohn's disease and ulcerative colitis) versus controls.
IBD, inflammatory bowel disease; NA, not applicable; NS, not significant.