Macroscopic phenotype of the diethylnitrosamine liver tumour model in the different knockout mouse strains in comparison with wild-type animals
| D6−/− | Rag1−/− | Igh6−/− | MHCII−/− | |
| Immunological phenotype | Macrophage increase | Lack of T and B cells | Lack of B cells | Lack of CD4 T cells and dendritic cells |
| Number of tumours | = | + | = | = |
| Size of tumours | = | + | ++ | (+) |
| Overall tumour burden | = | ++ | + | = |