Patients with both central and local readings at baseline and week 10 (n=44) | Patients with both central and local readings at baseline and week 54 (n=28) | |||
Central reading | Local reading | Central reading | Local reading | |
Baseline CDEIS: mean±SD | 10.9±4.5 | 14.7±5.9 | 10.8±5.2 | 15.1±5.9 |
CDEIS at time point: mean±SD | 7.1±4.5 | 8.5±6.4 | 7.9±5.8 | 9.3±6.2 |
CDEIS decrease: mean (95% CI) | 3.8 (2.5 to 5.1) | 6.2 (4.5 to 8.5) | 3.0 (0.2 to 5.7) | 5.7 (2.8 to 8.6) |
Endoscopic response: % of patients (95% CI) | 39 (24 to 55) | 59 (43 to74) | 39 (22 to 59) | 61 (41 to 79) |
Endoscopic remission: % of patients (95% CI) | 46 (30 to 61) | 39 (24 to 55) | 32 (16 to 52) | 29 (13 to 49) |
Complete endoscopic remission: % of patients (95% CI) | 21 (10 to 35) | 14 (5 to 27) | 18 (6 to 37) | 21 (8 to 41) |
CDEIS, Crohn's Disease Endoscopic Index of Severity.