Table 3

Comparison of central and local readings in patients with both evaluations at baseline/week 10 and at baseline/week 54

Patients with both central and local readings at baseline and week 10 (n=44)Patients with both central and local readings at baseline and week 54 (n=28)
Central readingLocal readingCentral readingLocal reading
Baseline CDEIS: mean±SD10.9±4.514.7±5.910.8±5.215.1±5.9
CDEIS at time point: mean±SD7.1±4.58.5±6.47.9±5.89.3±6.2
CDEIS decrease: mean (95% CI)3.8 (2.5 to 5.1)6.2 (4.5 to 8.5)3.0 (0.2 to 5.7)5.7 (2.8 to 8.6)
Endoscopic response: % of patients (95% CI)39 (24 to 55)59 (43 to74)39 (22 to 59)61 (41 to 79)
Endoscopic remission: % of patients (95% CI)46 (30 to 61)39 (24 to 55)32 (16 to 52)29 (13 to 49)
Complete endoscopic remission: % of patients (95% CI)21 (10 to 35)14 (5 to 27)18 (6 to 37)21 (8 to 41)
  • CDEIS, Crohn's Disease Endoscopic Index of Severity.