Table 5

Toxicity events during 1st-line therapy (NCI-CTCv2.0)

ToxicityPercentage of patients
Gem+E (n=132)* Cap+E (n=124)*
GradeGrade
1234All1234All
Leucocytopenia23297160730010
Thrombocytopenia2014834531206
Anaemia21351126921155041
Infection9221444961212131
Diarrhoea2323615329209361
Nausea3030806824265055
Vomiting2118414413173134
Stomatitis9820192293034
Skin rash2532916731236161
Hand–foot syndrome82001019136038
Pneumonitis0020200000
  • Cap, capecitabine; E, erlotinib; Gem, gemcitabine.

  • * Safety population (n=256).