Table 2

Pancreatic juice GNAS status and clinical variables of 33 screened subjects with only diminutive pancreatic cyst(s)

Case	Risk group	Gender	Age	EUS findings						Detection of cysts by CT	Juice GNAS status
Case	Risk group	Gender	Age	No of cysts	Tumour location^*	Tumour size^* (mm)	Multiseptal	Duct communication	Mural nodule	Detection of cysts by CT	Mutation score^†	Codon 201
1	Familial	Male	46	1	Not recorded	4	ND	ND	ND	No	1	R201C
2	Familial	Female	80	4	Tail	3	ND	ND	Present	Yes	1	R201C
3	Familial	Female	50	1	Body	1	ND	ND	ND	Yes	1	R201C
4	Familial	Male	54	1	Body	4	ND	ND	ND	No	3	R201C
5	Familial	Female	59	2	Body	4	ND	ND	ND	No	1	R201C
6	Familial	Female	75	4	Head	4	ND	ND	ND	No	2	R201C
7	Familial	Male	62	1	Body	4	ND	Present	ND	No	2	R201C
8	Familial	Male	67	1	Body	4	ND	ND	ND	No	2	R201C
9	Familial	Female	64	2	Tail	4	ND	ND	Present	Yes	3	R201H
10	Familial	Male	66	2	Head	3	Present	ND	ND	No	3	R201H
11	Familial	Male	73	1	Tail	4	ND	ND	ND	No	3	R201H
12	Familial	Male	56	4	Head	3	ND	ND	ND	No	5	R201H
13	Familial	Female	60	3	Head	3	ND	ND	ND	No	2	R201H
14	Familial	Female	59	2	Head	4	ND	ND	ND	No	6	R201H
15	BRCA2^‡	Male	62	2	Body	4	ND	ND	ND	No	1	R201C
16	Familial	Male	43	5	Not recorded	4	ND	ND	ND	No	0	WT
17	Familial	Female	54	6	Body	4	ND	ND	ND	Yes	0	WT
18	Familial	Female	48	4	Tail	3	ND	ND	ND	Yes	0	WT
19	Familial	Male	54	2	Body	2	ND	ND	ND	No	0	WT
20	Familial	Male	61	1	Body	2	ND	ND	ND	No	0	WT
21	Familial	Male	50	1	Body	2	ND	ND	ND	No	0	WT
22	Familial	Female	55	1	Head	3	ND	ND	ND	No	0	WT
23	Familial	Male	63	1	Body	3	ND	ND	ND	No	0	WT
24	Familial	Male	70	1	Head	4	ND	Present	ND	No	0	WT
25	Familial	Female	54	1	Body	4	Present	ND	ND	No	0	WT
26	Familial	Male	61	2	Head	3	ND	ND	ND	No	0	WT
27	Familial	Male	60	1	Body	2	ND	Present	ND	No	0	WT
28	Familial	Male	71	1	Body	4	ND	ND	ND	No	0	WT
29	BRCA2^‡	Female	59	1	Tail	2	ND	ND	ND	No	0	WT
30	BRCA2^‡	Female	72	1	Body	2	ND	Present	ND	No	0	WT
31	BRCA2^‡	Male	49	2	Tail	2	ND	Present	ND	No	0	WT
32	p16^‡	Male	70	1	Body	4	ND	ND	ND	No	0	WT
33	PJS	Female	32	1	Tail	2	Present	ND	ND	No	0	WT

↵* Size of the largest cyst.
↵† Mutation score was calculated from total number of positive wells with confirmed GNAS mutations by pyrosequencing.
↵‡ Carriers of germline mutation.
EUS, endoscopic ultrasonography; ND, not detected; PJS, Peutz–Jeghers syndrome; WT, wild-type.