Outcome of colonoscopic surveillance in LS
| Author/year | No of participants | Mean follow-up (years) | Interval recommend (years) | Risk interval cancer* | No of interval cancers | Location right colon (%) | Local stage (stage I & II) (%) | Death CRC | |
|---|---|---|---|---|---|---|---|---|---|
| By follow-up time | By age 60 years | ||||||||
| Mecklin et al (2007)44 | 420 | 6.7 | 2 | – | M 35% F 22% | 26 | 57 | 80 | 5 |
| Engel et al (2010)46 | 1126 | 3.7 | 1 | – | – | 25 | Not reported | 95 | Not reported |
| Vasen et al (2010)45 | 745 | 7.2 | 1–2 | 6%/10 years | – | 33 | 62 | 83 | 0 |
| Stuckless et al (2011)47 | 109 | Ca 10 | 1–2 | – | – | 21 | 62 | 78 | 1 |
*Defined as CRC that develops after a negative screening colonoscopy.
CRC, colorectal cancer; LS, Lynch syndrome.