Table 1

Clinical and demographic characteristics of patients included in the study

UC activeUC remissionNon-IBD controls
COHORT 1 (microarray analysis)
 Number15813
 Gender (M/F)4/113/55/8
 Age (years)42.4±9.149.4±11.741.6±12.4
 Duration of disease (years)6.6±5.212.4±8.8
 Extension of disease*0/8/71/5/2
 Medication†4/8/1/25/3/0/0
COHORT 2 (Real-time RT-PCR)
 Number81210
 Gender (M/F)5/36/63/7
 Age (years)49.5±17.340.5±11.242.7±9.9
 Duration of disease (years)3.6±3.910.3±6.3
 Extension of disease*2/5/11/7/4
 Medication†3/1/1/32/5/0/5
COHORT 3 (immunohistochemistry analysis)
 Number797
 Gender (M/F)5/27/22/5
 Age (years)48±17.958.6±14.345.6±19.5
 Duration of disease (years)6.3±6.611.4±5.4
 Extension of disease*0/4/32/3/4
 Medication†1/5/1/04/4/0/1
  • *Proctitis/Left-sided colitis/Pancolitis.

  • †5ASA/Azathioprine/Steroids/no treatment.

  • IBD, inflammatory bowel disease; UC, ulcerative colitis.