Table 3

ESTs can detect eosinophilic inflammation without evidence of superficial inflammation

	Sample source	White exudate (8 without vs 6 with) p value*	Superficial layering (9 without vs 5 with) p value*	Microabscess (9 without vs 5 with) p value*
MBP1	Biopsies	0.6354	0.4457	0.0817
MBP1	ESTs	0.4921	0.0325	0.0430
EDN	Biopsies	0.0681	0.2850	0.2137
EDN	ESTs	0.3718	0.2475	0.5314
ECP	Biopsies	0.1573	0.1342	0.0384
ECP	ESTs	0.0507	0.7435	0.8338
EPX	Biopsies	0.1445	0.5722	0.7302
EPX	ESTs	0.5830	0.2279	0.3776
CLC/Gal-10	Biopsies	0.7754	0.6341	0.4833
CLC/Gal-10	ESTs	0.6070	0.2490	0.2881

Active EoE subjects (14) with or without evidence of superficial mucosal inflammation (noted in parentheses in table) were compared with each other for each of the eosinophil-derived proteins from each sample source (biopsy or EST).
* From two sample t tests comparing subjects with versus those without a particular endoscopic/histological condition. Statistically significant values (p<0.05) are in bold.
CLC/Gal-10, Charcot–Leyden crystal protein/galectin-10; ECP, eosinophil cationic protein; EDN, eosinophil-derived neurotoxin; EoE, eosinophilic oesophagitis; EPX, eosinophil peroxidase; EST, oesophageal string test; MBP1, major basic protein-1.