Table 3

Monitoring of Crohn's disease with blood C-reactive protein and faecal calprotectin

 ▸ Non-invasive  ▸ Good acceptance  ▸ Relatively low cost  ▸ Can be repeated as a longitudinal monitoring tool  ▸ May be combined to improve prediction  ▸ Predictive value for   – Disease relapse under or after medical therapy   – Response to anti-TNF treatment   – Mucosal healing ▸ Subject to non-specific variations  ▸ Stool marker not always well accepted by patients (faecal calprotectin)  ▸ The correlation with mucosal healing and transmural healing is imperfect  ▸ Predictive threshold values not fully established
  • TNF, tumour necrosis factor.