Admission characteristics of patients with extrapancreatic necrosis only (EXPN) compared with patients with pancreatic parenchymal necrosis
| Characteristic | All patients (N=639) | EXPN (N=315) | Pancreatic necrosis (N=324) | p Value |
|---|---|---|---|---|
| Age (years) | 58 (45–70) | 58 (44–72) | 58 (45–69) | 0.24† |
| Male sex | 398 (62%) | 184 (58%) | 214 (66%) | 0.05‡ |
| Aetiology | 0.26§ | |||
| Gallstones | 304 (48%) | 149 (47%) | 155 (48%) | |
| Alcohol abuse | 150 (24%) | 76 (24%) | 74 (23%) | |
| Other | 63 (10%) | 37 (12%) | 26 (8%) | |
| Unknown | 122 (19%) | 53 (17%) | 69 (21%) | |
| ASA class on admission | 0.79¶ | |||
| I (healthy status) | 202 (32%) | 97 (31%) | 105 (32%) | |
| II (mild systemic disease) | 347 (54%) | 174 (55%) | 173 (53%) | |
| III (severe systemic disease) | 90 (14%) | 44 (14%) | 46 (14%) | |
| Predicted severity of pancreatitis | ||||
| APACHE-II score on admission | 8 (5–11) | 7 (5–10) | 8 (5–11) | 0.98† |
| Imrie/modified Glasgow score after 48 h | 3 (2–5) | 3 (2–4) | 4 (2–5) | <0.001† |
| Highest CRP level in first 48 h | 291 (216–382) | 293 (216–278) | 290 (215–388) | 0.60† |
| Transferred from other hospital | 156 (24%) | 40 (13%) | 116 (36%) | <0.001‡ |
| No. of CECTs performed per patient* | 2 (4–7) | 2 (1–4) | 6 (3–10) | <0.001† |
| Timing of final CECT* (days after admission) | 14 (7–46) | 9 (5–21) | 34 (9–71) | <0.001† |
Continuous variables are median (IQR)
↵* Before discharge or any intervention.
↵† Mann–Whitney U test.
↵‡ Fisher exact test.
↵§ Pearson χ2 test.
↵¶ Linear-by-linear association.
APACHE, Acute Physiology Age and Chronic Health Evaluation; ASA, American Society of Anaesthesiologists; CECT, contrast-enhanced CT; CRP, C-reactive protein.