Risk of mortality due to colorectal cancer, gastric cancer, oesophageal cancer, and pancreatic cancer mortality (rare outcomes) in NHANES III in participants ≥40.1 years old
| HR and 95% CI for total and cause-specific mortality by H pylori/cagA status | HR and 95% CI for total and cause-specific mortality by H pylori status | ||||
|---|---|---|---|---|---|
| H pylori−cagA− | H pylori+cagA− | H pylori+cagA+ | H pylori− | H pylori+ | |
| Follow-up person years | 20469.9 | 12842.6 | 21838.8 | 20485.8 | 34681.3 |
| Colorectal cancer* | |||||
| Deaths, n | 11 | 11 | 20 | 11 | 31 |
| Model 1† | 1.0 | 0.59 (0.25 to 1.39) | 1.46 (0.50 to 4.28) | 1.0 | 1.08 (0.42 to 2.81) |
| p Value | 0.22 | 0.48 | 0.86 | ||
| Gastric cancer* | |||||
| Deaths, n | 16 (total events) | 16 (total events) | |||
| Model 1† | 1.0 | 40.37 (3.55 to 458.54) | 41.41 (4.09 to 419.48) | 1.0 | 40.95 (4.19 to 399.92) |
| p Value | 0.0045 | 0.0029 | 0.0026 | ||
| Oesophageal cancer* | |||||
| Deaths, n | 6 (total events) | 6 (total events) | |||
| Model 1† | 1.0 | 0.44 (0.05 to 3.84) | 0.24 (0.02 to 2.43) | 1.0 | 0.33 (0.04 to 3.01) |
| p Value | 0.44 | 0.22 | 0.31 | ||
| Pancreatic cancer* | |||||
| Deaths, n | 23 (total events) | 8 | 15 | ||
| Model 1† | 1.0 | 0.21 (0.05 to 0.91) | 0.95 (0.43 to 2.11) | 1.0 | 0.63 (0.28 to 1.40) |
| p Value | 0.039 | 0.890 | 0.24 | ||
*Total number of deaths was <5 for at least one Helicobacter pylori category and therefore only the total numbers of evens were shown per NHANES publication restrictions.
†HRs were adjusted for age and sex.
NHANES III, National Health and Nutrition Examination Survey III.