Table 1

Characteristics of cases and controls

ControlsCasesp Value
n=586n=49
Follow-up
 Median, years (IQR)6.8 (5.7–7.4)3.0 (2.0–5.3)<0.001
Endoscopies
 Median number (IQR)4 (4–5)3 (2–4)<0.001
Biopsies available
 Median number per endoscopy (IQR)7 (4–10)8 (6–12)0.042
 Total number10.3461781
Age
 Median, years (IQR)60 (53–69)65 (55–70)0.171
Sex
 Women160 (27%)9 (18%)0.174
 Men426 (73%)40 (82%)
Alcohol use
 Never68 (12%)6 (12%)0.969
 Former53 (9%)5 (10%)
 Current453 (79%)38 (78%)
Smoking
 Never190 (33%)12 (25%)0.464
 Former262 (46%)25 (50%)
 Current122 (21%)12 (25%)
NSAID use
 No401 (68%)35 (71%)0.664
 Yes185 (32%)14 (29%)
Reflux symptoms
 No401 (69%)30 (61%)0.230
 Yes176 (31%)19 (39%)
Barrett diagnosis
 ≤1999237 (41%)16 (33%)0.512
 2000–2002200 (34%)20 (41%)
 2003–2004143 (25%)13 (27%)
Barrett length
 Median, cm (IQR)4 (3–6)5 (4–8)0.004
Oesophagitis
 No476 (81%)35 (71%)0.096
 Yes110 (19%)14 (29%)
  • Patients with neoplastic progression were identified as cases and patients without neoplastic progression as controls.

  • Mann–Whitney U tests and χ2 tests were used to compare characteristics of cases and controls.

  • NSAID, non-steroidal anti-inflammatory drug.