Table 2

Correlations of eosinophil-derived protein concentrations from biopsy extracts and ESTs with histological measures of mucosal eosinophilia

Peak eosinophils*Mean eosinophils*EPX Staining Index*
A. Biopsiesr Value†p Valuer Value†p Valuer Value†p Value
MBP10.72559<0.00010.72003<0.00010.72052<0.0001
EDN0.78673<0.00010.79306<0.00010.75952<0.0001
ECP0.70621<0.00010.70804<0.00010.66968<0.0001
EPX0.61117<0.00010.61596<0.00010.60103<0.0001
CLC/Gal-100.66360<0.00010.66329<0.00010.65902<0.0001
EPX Staining Index*
B. ESTsr Value†p Value
MBP10.72170<0.0001
EDN0.47688<0.002
ECP0.20519NS
EPX0.54145<0.0002
CLC/Gal-100.72735<0.0001
  • * n=41 subjects for peak and mean eosinophil numbers and EPX index.

  • Spearman's rank correlation coefficient (r) for values from n=41 subjects.

  • CLC/Gal-10, Charcot–Leyden crystal protein/galectin-10; ECP, eosinophil cationic protein; EDN, eosinophil-derived neurotoxin; EPX, eosinophil peroxidase; EST, oesophageal string test; MBP1, major basic protein-1.