Table 2

Four lines of uPA/SCID mice from four different lots of human hepatocytes (donor) containing various SNP around the IL28B gene

uPA/SCID miceDonorRaceAgeGenderrs8103142rs12979860rs8099917
PXB miceAAfrican American5 YearsMaleCCTTTG
BCaucasian10 YearsFemaleCCTTTG
CHispanic2 YearsFemaleTTCCTT
DCaucasian2 YearsMaleTTCCTT
  • PXB mice; urokinase-type plasminogen activator/severe combined immunodeficiency (uPA/SCID) mice repopulated with approximately 80% human hepatocytes.

  • SCID, severe combined immunodeficient; SNP, single nucleotide polymorphism.