Haemodynamic effects of propranolol and carvedilol
| Baseline | Propranolol | Carvedilol | p Value* propranolol vs carvedilol | |
|---|---|---|---|---|
| N=104 | N=94 | N=67 | ||
| HVPG (mm Hg) | 20.5±4.0 | 18.1±3.8 | 16.4±2.8 | <0.01 |
| Change in HVPG (%) | N/A | −12±12 | −19±11 | <0.01 |
| MAP (mm Hg) | 101±14 | 88±14 | 83±14 | 0.457 |
| Change in MAP (%) | N/A | −11±14 | −14±14 | 0.452 |
| HR (bpm) | 83±15 | 62±10 | 66±10 | 0.203 |
| Change in HR (%) | N/A | −23±12 | −17±15 | 0.091 |
*p Value for Wilcoxon matched pairs test.
bpm, beats per minute; HR, heart rate; HVPG, hepatic venous pressure gradient; MAP, mean arterial pressure; N/A, not applicable.