Table 7

Sensitivity analyses confirming association between general practice elective gastroscopy rates and emergency route of diagnosis, major surgical resection and death at 12 month for 22 488 cases of oesophagogastric cancer

Emergency admissionMajor surgical resectionDeath within 12 months
Practice gastroscopy rate variableORCIp ValueORCIp ValueORCIp Value
Quintile of age-sex-adjusted rate
 Q5 (highest)111
  Q41.060.96 to 1.170.2140.860.77 to 0.960.0100.980.90 to 1.060.683
 Q31.231.12 to 1.36<0.0010.840.75 to 0.940.0031.070.98 to 1.170.087
 Q21.331.20 to 1.48<0.0010.840.75 to 0.950.0051.131.03 to 1.230.006
 Q1 (lowest)2.141.92 to 2.3<0.0010.820.72 to 0.930.0021.141.03 to 1.250.006
Quintile of age-specific rate (>55 years)
 Q5 (highest)111
 Q41.161.05 to 1.280.0020.880.79 to 0.980.0301.091.01 to 1.180.040
 Q31.281.16 to 1.42<0.0010.840.75 to 0.930.0021.151.06 to 1.250.001
 Q21.431.29 to 1.58<0.0010.820.73 to 0.920.0011.151.05 to 1.260.001
 Q1 (lowest)2.302.07 to 2.55<0.0010.830.73 to 0.940.0041.241.13 to 1.36<0.001
Age-sex-adjusted rate per 100 population*0.520.48 to 0.57<0.0011.171.07 to 1.290.0010.860.80 to 0.92<0.001
Age-specific rate per 100 population (>55 years)* gastroscopy rate0.690.66 to 0.72<0.0011.091.04 to 1.15<0.0010.900.87 to 0.94<0.001
  • ORs adjusted for age, gender, comorbidity and deprivation in four alternative logistic regression analyses.

  • Alternative models in which the original gastroscopy rate exposure variable (practice tertile) was replaced by: (1) quintile of age-sex-adjusted elective gastroscopy rate; (2) quintile of age-specific rate for adults >55 years of age; (3) continuous variable for actual age-sex-adjusted elective gastroscopy rate of the patient's general practice (expressed as rate per 100 population) or (4) continuous variable for actual age-specific rate for adults >55 years of age.

  • *For the continuous rate variables, the OR represents the change in odds per unit increase in gastroscopy rate (eg, an increase from 1 per 100 to 2 per 100 practice population per year).