Per-screenee detection rates at CTC and colonoscopy by the largest lesion demonstrated
| CTC (n=2731) | Colonoscopy (n=72 817) | p Value* | |
|---|---|---|---|
| Colorectal cancer (%) | 124† (4.5) | 6577 (9.0) | <0.0001 |
| 10 mm+ polyp (%) | 340 (12.4) | 14 992 (20.6) | <0.0001 |
| 10 mm+ adenoma (%) | 320 (11.7) | 13 571 (18.6) | <0.0001 |
| 6–9 mm polyp (%) | 119 (4.4) | 5773 (7.9) | <0.0001 |
| 6–9 mm adenoma (%) | 103 (3.8) | 5243 (7.2) | <0.0001 |
| ≤5 mm polyp (%) | 75 (2.7) | 16 085 (22.1) | <0.0001 |
| ≤5 mm adenoma (%) | 45 (1.6) | 10 870 (14.9) | <0.0001 |
| 6 mm+ adenoma or CRC (%) | 547 (20.0) | 25 391 (34.9) | <0.0001 |
| 10 mm+ adenoma or CRC (%) | 444 (16.3) | 20 148 (27.7) | <0.0001 |
| Advanced neoplasia (%) | 504 (18.5) | 23 830 (32.7) | <0.0001 |
For CTC, at each size threshold the number of screenees with a matched lesion at confirmatory testing (endoscopy or surgery) is reported. For colonoscopy, the size categories are the endoscopic size for polyps and histologic size for adenomas.
Probability value for χ2 test.
†10 additional screenees had no confirmatory testing but suspected CRC on CT.
CRC, colorectal cancer; CTC, CT colonography.