Abstract PTH-082 Table 1
Analyte (* log transformed analysis)Borderline NASHDefinite NASH
DerivationValidationDerivationValidation
NAS 0-2
n=50 (miR=26)
NAS 3-8
n=95
(miR=60)
NAS 0-2 n=25NAS 3-8
n=65
NAS 0-4
n=107
(miR=64)
NAS 5-8
n=39
(miR=22)
NAS 0-4
n=62
NAS 5-8
n=28
sFas (pg/ml)58476491 (p = 0.022)59235653 (p=NS)61506604 (p=NS)57065777 (p=NS)
CK18 M30* (U/L)132.43182.81 (p = 0.007)179.47275.23 (p = 0.001)146.55223.36 (p = 0.001)212.86331.59 (p < 0.001)
CK18 M65* (U/L)140.93231.21 (p = 0.001)167.92351.4 (p < 0.001)168.66291.74 (p = 0.001)239.88422.67 (p = 0.003)
HMGB1* (ng/ml)1.652.08 (p=NS)1.702.42 (p = 0.003)1.812.29 (p=NS)2.022.63 (p = 0.028)
miR-122* (/let7d snRNA)10.5715.58 (p = 0.028)7.7112.32 (p = 0.002)12.7717.54 (p=NS)9.7113.61 (p = 0.018)