TableĀ 1

Specificities of hepatocellular carcinoma (HCC) in cirrhosis with respect to cirrhosis lacking HCC at the time of transplant consideration

High pretransplant mortalityLow pretransplant mortality
High post-transplant long-term recoveryVariable post-transplant cure, depending on tumour stage at operation
Predictable outcome with no transplant through the MELD scoreComposite prognostic factors and variable biology influencing outcome
No competitive options beside transplantationCompetitive options in selected patients subgroups
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Urgency principle
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Utility principle