Characteristic | All patients | Crohn's disease | Ulcerative colitis |
---|---|---|---|
Number of cases | 138 | 82 | 56 |
Age, years | 41 [15] | 38 [13] | 45 [16] |
Gender | |||
Male | 65 (47.1%) | 36 (43.9%) | 29 (51.8%) |
Female | 73 (52.9%) | 46 (56.1%) | 27 (48.2%) |
Disease duration, years | 8 [9] | 9 [8] | 8 [9] |
Previous surgery | |||
Yes | 45 (32.6%) | 43 (52.4%) | 2 (3.6%) |
No | 93 (67.4%) | 39 (47.6%) | 54 (96.4%) |
Perianal disease (fistula) | |||
Yes | 20 (14.5%) | 20 (24.4%) | 0 (0.0%) |
No | 118 (85.5%) | 62 (75.6%) | 56 (100.0%) |
Stoma present | |||
Yes | 5 (3.6%) | 4 (4.9%) | 1 (1.8%) |
No | 133 (96.4%) | 78 (95.1%) | 55 (98.2%) |
Medication | |||
Topical 5-ASA | 11 (8.0%) | 0 (0.0%) | 11 (19.6%) |
Topical steroid | 5 (3.6%) | 0 (0.0%) | 5 (8.9%) |
Oral 5-ASA | 82 (59.4%) | 34 (41.5%) | 48 (85.7%) |
Oral corticosteroid | 16 (11.6%) | 6 (7.3%) | 10 (17.9%) |
Standard immunosuppressants | 61 (44.2%) | 44 (53.7%) | 17 (30.4%) |
Biological agent | 29 (21.0%) | 24 (29.3%) | 5 (8.9%) |
Dietary therapy (polymeric diet) | 5 (3.6%) | 5 (6.1%) | 0 (0.0%) |
Disease activity indices | |||
Harvey-Bradshaw index | n/a | 5 [5] | n/a |
Simple Clinical Colitis Activity index | n/a | n/a | 5 [4] |
Quality of life questionnaires | |||
EQ-5D utility score | 0.61 [0.34] | 0.60 [0.35] | 0.62 [0.33] |
EQ-5D visual analogue scale | 61 [23] | 63 [22] | 56 [25] |
UK-IBD-Q | 83 [19] | 84 [18] | 82 [22] |
Physician global assessment | |||
Remission | 49 (44.1%) | 27 (44.3%) | 22 (44.0%) |
Mild | 38 (34.2%) | 26 (42.6%) | 12 (24.0%) |
Moderate | 18 (16.2%) | 6 (9.8%) | 12 (24.0%) |
Severe | 6 (5.4%) | 2 (3.3%) | 4 (8.0%) |
Continuous variables expressed as mean [SD] and categorical variables as number (%) where appropriate).