Table 2

Predictive factors for HBsAg seroclearance

Multivariable analysis*
VariablesHR95% CIp Value
Age1.010.99 to 1.040.19
HBeAg positivity0.460.30 to 0.68<0.01
HBV DNA level (log10 IU/mL)0.610.56 to 0.65<0.01
ALT (>5×ULN)1.801.19 to 2.74<0.01
Albumin level (g/dL)0.800.56 to 1.130.20
Cirrhosis0.480.31 to 0.75<0.01
Antiviral agent (entecavir)0.300.09 to 1.000.05
  • The ULN of ALT was defined as 30 IU/L for men and 19 IU/L for women.

  • *Cox proportional hazard model.

  • ALT, alanine aminotransferase; ULN, upper limit of normal.