Whole gut and regional transit times (median (IQR))
| Whole gut transit time | Right colon | Left colon | Rectosigmoid | |
|---|---|---|---|---|
| Healthy controls N=19 | 46 (12–58) | 13 (5–18) | 12 (3–24) | 7 (4–15) |
| Patients with IBS-D on placebo | 16 (7–29)* | 6 (2–12) | 2.5 (0–7)*** | 4 (1–9)*** |
| Patients with IBS-D on ondansetron | 24 (15–47) | 7 (3–16) | 6 (0–17.25) | 7 (2–13) |
| P for difference on ondansetron | NS | <0.05 | <0.05 |
*p<0.05, ***p<0.001 versus healthy volunteers.
IBS-D, irritable bowel syndrome with diarrhoea.