Comparison of baseline characteristics of patients in the DR6 and SR6 groups
| Parameters Mean±SD; % (n) | The DR6 group (n=93) | The SR6 group (n=94) | p* Value |
|---|---|---|---|
| Female | 30.1 (28) | 23.4 (22) | 0.30 |
| Mean age (years) | 72.2±12.8 | 69.7±13.3 | 0.18 |
| The shock score on arrival† (n) | |||
| 0:1:2 | 42:30:21 | 34:37:23 | 0.44 |
| Ulcer characteristics | |||
| GU:DU and both (n) | 52:41 | 52:42 | 0.94 |
| Mean ulcer size (cm) | 1.28±1.06 | 1.31±1.12 | 0.85 |
| Forrest classification, Ia:Ib:IIa:IIb (n) | 2:31:47:13 | 1:32:46:15 | 0.92 |
| Rockall score (n) | |||
| 6:7:8:9:10 | 25:32:27:6:3 | 26:29:27:11:1 | 0.62 |
| Gastroscopic therapy at the first endoscopy‡ (n) | |||
| Epinephrine:mono:combination therapies | 12:8:73 | 14:15:65 | 0.25 |
| Gastroscopic therapy at the second endoscopy§ | 0 (0/12) | 28.6 (4/14) | 0.10 |
| ASA physical status classification (n) | |||
| Class I:II:III:IV | 0:30:53:10 | 0:25:56:13 | 0.63 |
| Helicobacter pylori infection | 47.1 (40/85) | 42.9 (33/77) | 0.59 |
| NSAID user | 48.4 (45) | 36.2 (34) | 0.09 |
| Antiplatelet agent user | 46.2 (43) | 39.4 (37) | 0.34 |
| Mean haemoglobin (g/L) | 89±24 | 85±24 | 0.24 |
| Platelet <50×109/L | 1.1 (1) | 3.2 (3) | 0.62 |
| PT prolonged ≥4 s | 12.9 (12) | 11.7 (11) | 0.80 |
| APTT prolonged ≥1.5-fold | 2.2 (2) | 1.1 (1) | 0.62 |
| Initial albumin <30 g/L | 35.5 (33) | 41.5 (39) | 0.40 |
*The Student t test, Pearson's χ2 test and Fisher's exact test with two-tailed analysis were used, as appropriate.
†The shock score is given according to the Rockall scoring system.
‡Gastroscopic combination therapies indicates at least two modalities for peptic ulcer haemostasis within one endoscopic session. Monotherapy indicates one modality, except epinephrine injection.
§Gastroscopic therapy at the second endoscopy was carried out for patients who received epinephrine injection only at the first endososcopy.
Haemoglobin: normal range 135–170 g/L; platelets: normal range: 138–353×109/L; albumin: normal range 30–50 g/L.
APTT, activated partial thromboplastin time; ASA, American Society of Anaesthesiology; DR6, oral double-dose group with Rockall scores ≥6; DU, duodenal ulcer; GU, gastric ulcer; NSAIDs, non-steroidal anti-inflammatory drugs; PT, prothrombin time; SR6, oral standard-dose group with Rockall scores ≥6.