Table 1

Characteristics of oesophageal adenocarcinoma (OAC) patients according to prior Barrett's oesophagus (BO) diagnosis

 Adenocarcinoma and histologically unspecified tumoursOesophageal adenocarcinoma only
All patients (n=716)Patients with no prior BO diagnosis (n=664)Patients with a prior BO diagnosis (n=52)p ValueAll patients (n=527)Patients with no prior BO diagnosis (n=485)Patients with a prior BO diagnosis (n=42)p Value
Age at cancer diagnosis (years), mean (SD)69.7 (12.4)69.9 (12.3)67.4 (13.2)0.1868.6 (12.3)68.8 (12.2)66.6 (13.1)0.26
Sex, n (%)
 Male525 (73.3)484 (72.9)41 (78.9)0.35404 (76.7)370 (76.3)34 (81.0)0.49
 Female191 (26.7)180 (27.1)11 (21.1)123 (23.3)115 (23.7)8 (19.0)
Tumour stage, n (%)
 Stage I4 (4.8)25 (3.7)9 (17.3)<0.00132 (6.1)23 (4.7)9 (21.4)<0.001
 Stage IIA43 (6.1)33 (5.0)10 (19.2)39 (7.4)30 (6.2)9 (21.4)
 Stage IIB20 (2.8)16 (2.4)4 (7.7)18 (3.4)14 (2.9)4 (9.5)
 Stage III93 (13.0)87 (13.1)6 (11.5)88 (16.7)83 (17.1)5 (11.9)
 Stage IV183 (25.6)178 (26.8)5 (9.6)136 (25.8)133 (27.4)3 (7.1)
 Unknown343 (47.9)325 (49.0)18 (34.6)214 (40.6)202 (41.7)12 (28.6)
Surgery, n (%)
 Resection195 (27.2)169 (25.5)26 (50.0)<0.001185 (35.1)159 (32.8)26 (61.9)<0.001
 No resection521 (72.8)495 (74.6)26 (50.0)342 (64.9)326 (67.2)16 (38.1)
Tumour grade, n (%)
 Low28 (3.9)23 (3.5)5 (9.6)0.01128 (5.3)23 (4.7)5 (11.9)0.025
 Intermediate172 (24.0)153 (23.0)19 (36.5)167 (31.7)148 (30.5)19 (45.2)
 High317 (44.3)301 (45.3)16 (30.8)248 (47.1)235 (48.5)13 (31.0)
 Unknown199 (27.8)187 (28.1)12 (23.1)84 (15.9)79 (16.3)5 (11.9)