Table 1

Haematological, iron and inflammation parameters of patients at baseline and 6 h after hypoxia

Timep Value
ParameterBaselineAfter 6 h of hypoxiaTime course
Female/male (N=23)10/13
Age (years)27.7±6.4
pO2 (mm Hg)96.3±13.0 (N=14)45.8±7.1 (N=17)<0.001
SO2 (%)96.8±0.967.1±12.1<0.001
Haemoglobin (g/dL)13.8±1.814.2±1.30.221
Serum iron (μmol/L)19.2±7.617.7±6.20.132
Transferrin (mg/dL)318±51317±610.953
Transferrin saturation (%)24.2±9.423.0±9.40.350
Serum ferritin (ng/mL)100±73114±860.197
sTfR (mg/L)3.30±0.843.30±0.760.966
C reactive protein (nmol/L)1540±38032105±63630.633
Serum IL-6 (pg/mL)2.43±3.9912.09±19.32<0.001
Serum TNF (pg/mL)2.09±1.032.09±0.950.924
Serum TGF-β (ng/mL)34.95±8.2335.97±9.130.438
sVEGF-R (pg/mL)83.5±16.7129.3±40.4<0.001
Serum EPO (mU/mL)10.1±3.721.5±6.0<0.001
  • Significant p values are indicated in bold.

  • Data are shown as means±SD.

  • p Values for time courses are shown as determined by paired t test or Wilcoxon test. p Value<0.05 was considered to be significant. Conversion factors for units: serum iron in μg/dL to μmol/L ×0.179; C reactive protein in mg/dL to nmol/L ×95.2.

  • EPO, erythropoietin; IL-6, interleukin 6; pO2, oxygen pressure; SO2, oxygen saturation; sTfR, soluble transferrin receptor; sVEGF-R, soluble vascular endothelial growth factor receptor; TGF-β, transforming growth factor β; TNF, tumour necrosis factor.