SNP | Chr | Position | Allele | P_trend | MAF achalasia | MAF HV | OR (95% CI) |
---|---|---|---|---|---|---|---|
rs929138 | 6 | 31611677 | G/A | 5.22E-01 | 0.24 | 0.28 | 0.82 (0.45 to 1.48) |
rs2239705 | 6 | 31621381 | T/C | 4.31E-02 | 0.20 | 0.17 | 1.22 (1.01 to 1.49) |
rs2523500 | 6 | 31626333 | C/T | 4.97E-01 | 0.36 | 0.34 | 1.06 (0.91 to 1.24) |
rs6916921 | 6 | 31628405 | T/C | 4.40E-03 | 0.13 | 0.10 | 1.42 (1.12 to 1.80) |
rs116749187 | 6 | 31637876 | T/C | 4.73E-01 | 0.13 | 0.17 | 0.78 (0.40 to 1.52) |
rs2857602 | 6 | 31641357 | C/T | 3.19E-01 | 0.41 | 0.39 | 1.08 (0.93 to 1.26) |
rs2844484 | 6 | 31644203 | T/C | 3.37E-01 | 0.41 | 0.39 | 1.08 (0.92 to 1.30) |
rs2844483 | 6 | 31644775 | A/C | 2.67E-01 | 0.41 | 0.48 | 0.74 (0.44 to 1.26) |
rs2071590 | 6 | 31647747 | T/C | 2.37E-01 | 0.35 | 0.43 | 0.72 (0.42 to 1.23) |
rs2239704 | 6 | 31648120 | T/G | 3.63E-01 | 0.41 | 0.39 | 1.07 (0.92 to 1.26) |
rs769178 | 6 | 31655493 | A/C | 2.06E-03 | 0.13 | 0.10 | 1.46 (1.15 to 1.85) |
rs3132452 | 6 | 31671219 | T/G | 5.04E-01 | 0.13 | 0.17 | 0.77 (0.37 to 1.62) |
rs1046089 | 6 | 31710946 | A/G | 7.74E-04 | 0.29 | 0.35 | 0.76 (0.64 to 0.89) |
Shown from left to right are: National Center for Biotechnology Information (NCBI) dbSNP database accession numbers (SNP), chromosome and chromosomal position (Chrom, Position), two nucleotides of the SNP, first allele is the minor allele (Allele), Armitage's trend test (P_trend), frequency of the minor allele in achalasia patients (MAF achalasia) and HVs (MAF HV), OR and 95% CI.
HV, healthy volunteer; LD, linkage disequilibrium; MAF, minor allele frequency; SNP, single nucleotide polymorphism.