Survival analysis of oesophageal adenocarcinoma (OAC) patients according to prior Barrett's oesophagus (BO), sex and tumour grade categories
| Adenocarcinoma and histologically unspecified tumours | Oesophageal adenocarcinoma only | |||||||
|---|---|---|---|---|---|---|---|---|
| All patients (n=716) | Number of deaths (n=610) | Unadjusted HR (95% CI) | Adjusted* HR (95% CI) | All patients (n=527) | Number of deaths (n=435) | Unadjusted HR (95% CI) | Adjusted* HR (95% CI) | |
| Prior BO diagnosis, n (%) | ||||||||
| No | 664 | 582 (87.7) | 1.00 | 1.00 | 485 (92.0) | 416 (95.6) | 1.00 | 1.00 |
| Yes | 52 | 28 (53.8) | 0.39 (0.27 to 0.58) | 0.44 (0.30 to 0.64) | 42 (8.0) | 19 (4.4) | 0.32 (0.20 to 0.51) | 0.34 (0.21 to 0.54) |
| Sex, n (%) | ||||||||
| Male | 525 | 440 (83.8) | 1.00 | 1.00 | 404 (76.7) | 326 (74.9) | 1.00 | 1.00 |
| Female | 170 | 241 (89.0) | 1.31 (1.09 to 1.56) | 1.13 (0.94 to 1.35) | 123 (23.3) | 109 (25.1) | 1.30 (1.05 to 1.62) | 1.15 (0.92 to 1.44) |
| Tumour grade, n (%) | ||||||||
| Low or intermediate | 189 | 144 (76.2) | 1.00 | 1.00 | 142 (26.9) | 142 (32.6) | 1.00 | 1.00 |
| High | 303 | 266 (87.8) | 1.46 (1.19 to 1.78) | 1.38 (1.14 to 1.69) | 246 (46.7) | 212 (48.7) | 1.32 (1.07 to 1.63) | 1.25 (1.01 to 1.55) |
| Unknown | 224 | 200 (89.3) | 1.84 (1.49 to 2.29) | 1.56 (1.25 to 1.95) | 94 (17.8) | 81 (18.6) | 1.39 (1.05 to 1.84) | 1.17 (0.88 to 1.55) |
*Adjusted for age at cancer diagnosis (years, continuous), sex (categorical) and tumour grade (categorical).