Baseline faecal weight and pH, and daily output of short-chain fatty acids (SCFA) and phenols in patients with UC (n=14) and control subjects (n=10) from the second part of the study (see matched dietary intake in online supplementary table S2)
| Faecal variable | Control | UC | p Value |
|---|---|---|---|
| Faecal weight (g/day) | |||
| Wet | 168 (123 to 213) | 182 (140 to 224) | ns |
| Dry | 45 (33 to 58) | 44 (35 to 53) | ns |
| Faecal pH | 6.8 (6.7 to 7.0) | 6.8 (6.6 to 7.0) | ns |
| Carbohydrate content (g/day) | |||
| Starch | 0.45 (0.3 to 0.6) | 1.32 (0.9 to 1.8) | 0.003 |
| NSP | 3.52 (2.9 to 4.4) | 9.78 (5.8 to 13) | 0.009 |
| Phenols output (mg/day) | |||
| Phenol | 0.13 (0.05 to 122) | 0.09 (0.04 to 1.3) | ns |
| p-Cresol | 2.8 (1.3 to 4.3) | 2.4 (1.2 to 3.5) | ns |
| SCFA output (mmol/day) | |||
| Total | 13.46 (9.28 to 17.63) | 14.94 (8.76 to 21.11) | 0.67 |
| Acetate | 7.78 (5.31 to 10.25) | 8.51 (4.89 to 12.13) | 0.73 |
| Propionate | 2.38 (1.37 to 3.39) | 2.66 (1.69 to 3.63) | 0.66 |
| Isobutyrate | 0.24 (0.15 to 0.33) | 0.23 (0.10 to 0.36) | 0.91 |
| Butyrate | 2.04 (1.42 to 2.68) | 2.81 (1.43 to 4.19) | 0.31 |
| Isovalerate | 0.35 (0.19 to 0.50) | 0.32 (0.13 to 0.51) | 0.79 |
| Valerate | 0.52 (0.29 to 0.76 | 0.39 (0.20 to 0.59) | 0.36 |
| Caproate | 0.15 (0.01 to 0.29) | 0.02 (0.0009 to 0.04) | 0.03 |
Data are shown as mean (95% CI) and p values calculated using a Euclidian distance matrix and differences were calculated performing a one-way Permanova analysis. Statistical significance was represented by p≤0.05.
NSP, non-starch polysaccharide.