Table 5

Association results (A) and comparison (B) of extreme groups in the pancreatitis cohort vs healthy blood donors

BDPanCPAPICPACP
(A)
Blood group B (G1) vs remaining (G0)
G1180171100714039
G01311871437434189175
Non-secretor (G1) vs secretor (G0)
G1233186113735438
G01258795389406172156
Blood group B and non-secretor (G1) vs remaining (G0)
G1302517866
G01461956485471220188
Blood group B vs non-BNon-secretor vs secretorBlood group B and non-secretor vs remaining
PVALOR (95% CI)PVALOR (95% CI)PVALOR (95% CI)
(B)
Pan vs BD0.00231.43 (1.14 to 1.79)0.03521.26 (1.02 to 1.56)0.45621.27 (0.74 to 2.18)
CP vs BD2.2×1041.67 (1.28 to 2.18)7.2×10−71.57 (1.22 to 2.02)0.11291.71 (0.93 to 3.12)
AP vs BD0.27741.19 (0.89 to 1.6)0.89580.97 (0.73 to 1.29)0.77760.83 (0.38 to 1.82)
ICP vs BD0.03001.54 (1.06 to 2.24)0.00261.70 (1.21 to 2.379)0.70441.33 (0.55 to 3.23)
ACP vs BD0.01611.26 (1.11 to 2.37)0.19071.32 (0.9 to 1.93)0.47441.55 (0.64 to 3.78)
  • ACP, alcoholic chronic pancreatitis; AP, acute pancreatitis; BD, blood donor cohort; CP, chronic pancreatitis; ICP, idiopathic chronic pancreatitis; Pan, total pancreatitis cohort; PVAL, p value (χ2 test).

  • 95% CI, 95% CI of OR, grey shaded cells are nominal significant (PVAL<0.05) and red shaded cells are significant after Bonferroni correction for 15 tests (PVAL<0.05/15 = 0.003). Genotyping of SNPs was performed by TaqMan analysis or genomic sequencing.