Absolute values for proximal oesophageal pain thresholds before (T0) and after (T60, T90 and T120) acid infusion with deep breathing and (a) placebo or (b) atropine
| T0 | T60 | T90 | T120 | |
|---|---|---|---|---|
| a. Pain threshold in study subjects with deep breathing/placebo | ||||
| Pain thresholds (mean, SD, mA) | 52.4 (15.2) | 48.2 (14.0) | 47.9 (11.0) | 48.3 (12.3) |
| b. Pain threshold in study subjects with deep breathing/atropine | ||||
| Pain thresholds (mean, SD, mA) | 54.4 (15.7) | 41.3 (15.0) | 42.3 (14.4) | 45.4 (14.7) |
Mixed effects regression showed a significant effect for atropine (coefficient −3.5 mA/unit time (CI −6.8 to −0.06), p=0.046).